North Carolina - Number and Rate of Fatal Drug Overdose Deaths By Type of Drug in 2023 (CDC)

Updated on February 2, 2026.

According to data from the CDC, the overall number of fatal drug overdose deaths in North Carolina for all drugs was 4,264, and the age adjusted overdose death rate per 100,000 persons was 40.2. The following types of drugs were among the drugs that were involved with high number of overdose deaths: Any Opioids (3,618), Illegally-made Fentanyls (3,358), Any stimulants (2,796), and Cocaine (1,734).

The chart below shows the age-adjusted rate of overdose deaths per 100K by type of drug. The table below shows the number and the overdose death rate by type of drug.

You can see similar information for other states and for the whole United States.

Note: A rate value of 9999 denotes that the value is suppressed. Rates based on less than 20 drug overdose deaths are suppressed to avoid presentation of unstable rates.

Data Source: CDC (SUDORS).
See this for other years:
North Carolina - Age-Adjusted Rate of Fatal Drug Overdose Deaths Per 100K Persons By Type of Drug in 2023
Any Opioids
Illegally-made Fentanyls
Any stimulants
Cocaine
Methamphetamine
Any non-opioid sedatives
Prescription Opioids
Benzodiazepines
Heroin
North Carolina - Number and Rate of Fatal Drug Overdose Deaths By Type of Drug in 2023
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Type of Drug Number of Overdose Deaths Age Adjusted Overdose Death Rate Per 100K
All Drugs 4264 40.2
Any Opioids 3618 34.3
Illegally-made Fentanyls 3358 31.9
Heroin 114 1.1
Prescription Opioids 509 4.8
Any stimulants 2796 26.4
Cocaine 1734 16.2
Methamphetamine 1296 12.3
Any non-opioid sedatives 791 7.5
Benzodiazepines 434 4.1