North Carolina - Number and Rate of Fatal Drug Overdose Deaths By Type of Drug in 2022 (CDC)

Updated on February 2, 2026.

According to data from the CDC, the overall number of fatal drug overdose deaths in North Carolina for all drugs was 4,087, and the age adjusted overdose death rate per 100,000 persons was 39.3. The following types of drugs were among the drugs that were involved with high number of overdose deaths: Any Opioids (3,572), Illegally-made Fentanyls (3,296), Any stimulants (2,553), and Cocaine (1,545).

The chart below shows the age-adjusted rate of overdose deaths per 100K by type of drug. The table below shows the number and the overdose death rate by type of drug.

You can see similar information for other states and for the whole United States.

Note: A rate value of 9999 denotes that the value is suppressed. Rates based on less than 20 drug overdose deaths are suppressed to avoid presentation of unstable rates.

Data Source: CDC (SUDORS).
See this for other years:
North Carolina - Age-Adjusted Rate of Fatal Drug Overdose Deaths Per 100K Persons By Type of Drug in 2022
Any Opioids
Illegally-made Fentanyls
Any stimulants
Cocaine
Methamphetamine
Any non-opioid sedatives
Prescription Opioids
Benzodiazepines
Heroin
North Carolina - Number and Rate of Fatal Drug Overdose Deaths By Type of Drug in 2022
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Type of Drug Number of Overdose Deaths Age Adjusted Overdose Death Rate Per 100K
All Drugs 4087 39.3
Any Opioids 3572 34.4
Illegally-made Fentanyls 3296 31.8
Heroin 157 1.5
Prescription Opioids 477 4.6
Any stimulants 2553 24.6
Cocaine 1545 14.8
Methamphetamine 1218 11.8
Any non-opioid sedatives 767 7.4
Benzodiazepines 351 3.4