North Carolina - Number and Rate of Fatal Drug Overdose Deaths By Gender and Race and Ethnicity in 2021 (CDC)

Updated on February 5, 2026.

According to data from the CDC, the overall number of fatal drug overdose deaths in North Carolina for all drugs was 3,854, and the age adjusted overdose death rate per 100,000 persons was 37.5.

Gender: The number of fatal drug overdose deaths was the following by gender: Males (2,690), and Females (1,164).

Race and Ethnicity: The number of fatal drug overdose deaths included the following by race and ethnicity: Non Hispanic White (2,677), Non Hispanic Black or African American (856), and Hispanic or Latino (170).

The first chart below shows the age-adjusted rate of overdose deaths per 100K by gender. And the first table shows the number and rate by gender. The second chart shows the age-adjusted rate of overdose deaths per 100K by race and ethnicity. And the second table shows the number and rate by race and ethnicity.

You can see similar information for other states and for the whole United States.

Data Source: CDC (SUDORS).
See this for other years:
North Carolina - Age-Adjusted Rate of Fatal Drug Overdose Deaths Per 100K Persons By Gender in 2021
Males
Females
North Carolina - Number and Age-Adjusted Rate of Fatal Drug Overdose Deaths Per 100K By Gender in 2021
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Gender Number of Overdose Deaths Age Adjusted Overdose Death Rate Per 100K
Males 2690 53.1
Females 1164 22.4

The chart and table below shows the number and rate of drug overdose deaths by race and ethnicity.

North Carolina - Age-Adjusted Rate of Fatal Drug Overdose Deaths Per 100K Persons By Race and Ethnicity in 2021
NH AIAN
NH White
NH Black or AA
Hispanic
NH Multi Race
North Carolina - Number and Rate of Fatal Drug Overdose Deaths By Race and Ethnicity in 2021
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Race and Ethnicity Number of Overdose Deaths Age Adjusted Overdose Death Rate Per 100K
Non Hispanic White 2677 42.7
Non Hispanic Black or African American 856 37.9
Hispanic or Latino 170 16.3
Non Hispanic American Indian or Alaska Native 112 96.1
Non Hispanic Two or More Races 26 13.7
Non Hispanic Asian 10 9999
Non Hispanic Native hawaiian or Pacific Islander 1 9999