VR ADVISER, LLC - Stock Holdings in 13F Filings (SEC)
Updated on March 15, 2026.
Based on 13F Filings filed with the SEC on February 17, 2026, for the 2025 Q4 period, VR ADVISER, LLC held in its portfolio 27 assets valued at $2,024,517,832 (i.e. $2.03B).
The most valuable assets in the portfolio included: APOGEE THERAPEUTICS INC ($641.08M), ORUKA THERAPEUTICS INC ($125.74M), and VIRIDIAN THERAPEUTICS INC ($120.83M).
The chart below shows the top 10 valuable assets, and the table below shows the top 27 valuable assets.
You can see similar for other investment managers.
Related Topics: SEC Topic List.
Data Source: SEC.
VR ADVISER, LLC - Stock Holdings in 13F Filings (SEC)
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| Name of Issuer | No. of Shares | Value ($) | Class |
|---|---|---|---|
| APOGEE THERAPEUTICS INC | 8493321 | 641075869 | COM |
| ORUKA THERAPEUTICS INC | 4148428 | 125738853 | COM |
| VIRIDIAN THERAPEUTICS INC | 3882709 | 120829904 | COM |
| SPYRE THERAPEUTICS INC | 3685448 | 120735276 | COM NEW |
| KALVISTA PHARMACEUTICALS INC | 6728985 | 108673108 | COM |
| OCULAR THERAPEUTIX INC | 7315547 | 88810741 | COM |
| SAVARA INC | 13740375 | 82854461 | COM |
| COGENT BIOSCIENCES INC | 2000000 | 71040000 | COM |
| ERASCA INC | 17857083 | 66428349 | COM |
| CYTOMX THERAPEUTICS INC | 15561500 | 66291990 | COM |
| MAZE THERAPEUTICS INC | 1548569 | 64157214 | COM |
| JADE BIOSCIENCES INC | 3220364 | 49690217 | COM NEW |
| ENLIVEN THERAPEUTICS INC | 3226331 | 49685497 | COM |
| ORIC PHARMACEUTICALS INC | 5676230 | 46431561 | COM |
| ENGENE HOLDINGS INC | 4771414 | 43085868 | COM |
| DYNE THERAPEUTICS INC | 2173913 | 42521738 | COM |
| DIANTHUS THERAPEUTICS INC | 1000000 | 41210000 | COM |
| UPSTREAM BIO INC | 1169298 | 31746441 | COM |
| CYBIN INC | 3840250 | 31413245 | COM NEW |
| ZURA BIO LTD | 5345115 | 28008403 | CLASS A ORD SHS |
| VOR BIOPHARMA INC | 1943766 | 25424459 | COM NEW |
| CRESCENT BIOPHARMA INC. | 2133576 | 25304211 | COM |
| SEPTERNA INC | 610808 | 17029327 | COM |
| SURROZEN INC | 632931 | 14304241 | COM NEW |
| CULLINAN THERAPEUTICS INC | 1379965 | 14282638 | COM |
| ARTIVA BIOTHERAPEUTICS INC | 1609569 | 6905051 | COM |
| CASI PHARMACEUTICALS INC | 987259 | 839170 | ORD SHS |
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