TRV GP V, LLC - Stock Holdings in 13F Filings (SEC)

Updated on March 15, 2026.

Based on 13F Filings filed with the SEC on February 13, 2026, for the 2025 Q4 period, TRV GP V, LLC held in its portfolio 3 assets valued at $429,165,290 (i.e. $429.17M).

The most valuable assets in the portfolio included: RAPPORT THERAPEUTICS, INC. ($216.48M), SEPTERNA, INC. ($173.29M), and MAZE THERAPEUTICS, INC. ($39.39M).

The chart below shows the top 3 valuable assets, and the table below shows the top 3 valuable assets.

You can see similar for other investment managers.

Related Topics: SEC Topic List.

Data Source: SEC.

Top Valuable Stocks in TRV GP V, LLC Portfolio

RAPPORT THERAPEUTICS, INC.

SEPTERNA, INC.

MAZE THERAPEUTICS, INC.

TRV GP V, LLC - Stock Holdings in 13F Filings (SEC)

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Name of Issuer	No. of Shares	Value ($)	Class
RAPPORT THERAPEUTICS, INC.	7135233	216482969	COM
SEPTERNA, INC.	6215591	173290677	COM
MAZE THERAPEUTICS, INC.	950800	39391644	COM