Spruce Street Capital LP - Stock Holdings in 13F Filings (SEC)
Updated on March 15, 2026.
Based on 13F Filings filed with the SEC on February 13, 2026, for the 2025 Q4 period, Spruce Street Capital LP held in its portfolio 27 assets valued at $302,659,606 (i.e. $302.66M).
The most valuable assets in the portfolio included: CIDARA THERAPEUTICS INC ($51.31M), RELAY THERAPEUTICS INC ($25.25M), and LB PHARMACEUTICALS INC ($22.39M).
The chart below shows the top 10 valuable assets, and the table below shows the top 27 valuable assets.
You can see similar for other investment managers.
Related Topics: SEC Topic List.
Data Source: SEC.
Spruce Street Capital LP - Stock Holdings in 13F Filings (SEC)
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| Name of Issuer | No. of Shares | Value ($) | Class |
|---|---|---|---|
| CIDARA THERAPEUTICS INC | 232269 | 51305899 | COM NEW |
| RELAY THERAPEUTICS INC | 2984125 | 25245698 | COM |
| LB PHARMACEUTICALS INC | 1005593 | 22384500 | COM SHS |
| RELMADA THERAPEUTICS INC | 4086181 | 19736254 | COM |
| VAXCYTE INC | 400360 | 18472610 | COM |
| KINIKSA PHARMACEUTICALS INTL | 434982 | 17943008 | ORD SHS CL A |
| EYEPOINT INC | 981543 | 17932791 | COM NEW |
| SAVARA INC | 2411093 | 14538891 | COM |
| ERASCA INC | 3889632 | 14469431 | COM |
| DIANTHUS THERAPEUTICS INC | 297437 | 12257379 | COM |
| SURROZEN INC | 432040 | 9764104 | COM NEW |
| OCULAR THERAPEUTIX INC | 783999 | 9517748 | COM |
| SAB BIOTHERAPEUTICS INC | 2198502 | 8222397 | COM NEW |
| INHIBIKASE THERAPEUTICS INC | 3581603 | 7342286 | COM NEW |
| ENLIVEN THERAPEUTICS INC | 446084 | 6869694 | COM |
| MINERVA NEUROSCIENCES INC | 1655500 | 6655110 | COM NEW |
| ABIVAX SA | 49119 | 6623943 | SPONSORED ADS |
| CYBIN INC | 770000 | 6298600 | COM NEW |
| KALVISTA PHARMACEUTICALS INC | 387968 | 6265683 | COM |
| ENANTA PHARMACEUTICALS INC | 389687 | 6145364 | COM |
| ALTO NEUROSCIENCE INC | 222844 | 3966623 | COM SHS |
| ATHIRA PHARMA INC | 393701 | 2980317 | COM |
| CENTESSA PHARMACEUTICALS PLC | 77997 | 1950705 | SPONSORED ADS |
| ALECTOR INC | 1117986 | 1744058 | COM |
| LEXEO THERAPEUTICS INC | 175000 | 1737750 | COM |
| CENTURY THERAPEUTICS INC | 1421532 | 1414140 | COM |
| SUTRO BIOPHARMA INC | 75594 | 874623 | COM SHS |
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