Soleus Capital Management, L.P. - Stock Holdings in 13F Filings (SEC)
Updated on March 15, 2026.
Based on 13F Filings filed with the SEC on February 12, 2026, for the 2025 Q4 period, Soleus Capital Management, L.P. held in its portfolio 95 assets valued at $2,710,906,126 (i.e. $2.71B).
The most valuable assets in the portfolio included: SPDR SERIES TRUST ($353.60M), KRYSTAL BIOTECH INC ($232.01M), and CELCUITY INC ($180.36M).
The chart below shows the top 10 valuable assets, and the table below shows the top 95 valuable assets.
You can see similar for other investment managers.
Related Topics: SEC Topic List.
Data Source: SEC.
Soleus Capital Management, L.P. - Stock Holdings in 13F Filings (SEC)
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| Name of Issuer | No. of Shares | Value ($) | Class |
|---|---|---|---|
| SPDR SERIES TRUST | 2900000 | 353597000 | STATE STREET SPD |
| KRYSTAL BIOTECH INC | 941059 | 232008686 | COM |
| CELCUITY INC | 1808258 | 180355653 | COM |
| NOVOCURE LTD | 8530665 | 110301498 | ORD SHS |
| PRAXIS PRECISION MEDICINES I | 362966 | 106980599 | COM NEW |
| TG THERAPEUTICS INC | 3139312 | 93582891 | COM |
| DEXCOM INC | 1297094 | 86088129 | COM |
| BIOMARIN PHARMACEUTICAL INC | 1320000 | 78447600 | COM |
| GLOBUS MED INC | 887000 | 77443970 | CL A |
| BETA BIONICS INC | 2534565 | 77228196 | COM |
| AMICUS THERAPEUTICS INC | 5207284 | 74151724 | COM |
| TWIST BIOSCIENCE CORP | 1861802 | 59056359 | COM |
| ORGANOGENESIS HLDGS INC | 9985951 | 51727226 | COM |
| SYNDAX PHARMACEUTICALS INC | 2247110 | 47211781 | COM |
| MIRUM PHARMACEUTICALS INC | 573614 | 45309770 | COM |
| INSULET CORP | 150000 | 42636000 | COM |
| NEUROPACE INC | 2703208 | 41737532 | COM |
| AXOGEN INC | 1206855 | 39500364 | COM |
| ANI PHARMACEUTICALS INC | 486243 | 38384022 | COM |
| ALKERMES PLC | 1322364 | 36999745 | SHS |
| LIVANOVA PLC | 567500 | 34918275 | SHS |
| GSK PLC | 639000 | 31336560 | SPONSORED ADR |
| GERON CORP | 23290000 | 30742800 | COM |
| UNITED THERAPEUTICS CORP DEL | 60000 | 29235000 | COM |
| IMMUNOVANT INC | 1110000 | 28216200 | COM |
| VAXCYTE INC | 608958 | 28097322 | COM |
| ALNYLAM PHARMACEUTICALS INC | 70000 | 27835500 | COM |
| INSPIRE MED SYS INC | 299399 | 27613570 | COM |
| VERICEL CORP | 764000 | 27511640 | COM |
| ARGENX SE | 31726 | 26679980 | SPONSORED ADR |
| RAPT THERAPEUTICS INC | 764000 | 25876680 | COM NEW |
| NEUROCRINE BIOSCIENCES INC | 175982 | 24959527 | COM |
| KINIKSA PHARMACEUTICALS INTL | 587000 | 24213750 | ORD SHS CL A |
| EDAP TMS S A | 7309254 | 24047446 | SPONSORED ADR |
| TELEFLEX INCORPORATED | 190000 | 23187600 | COM |
| NURIX THERAPEUTICS INC | 1219394 | 23131904 | COM |
| EDGEWISE THERAPEUTICS INC | 910000 | 22581650 | COM |
| INHIBIKASE THERAPEUTICS INC | 10875000 | 22293750 | COM NEW |
| PHARVARIS N V | 702052 | 19481943 | COM |
| INVIVYD INC | 7708727 | 19040556 | COM |
| CAPRICOR THERAPEUTICS INC | 646390 | 18654815 | COM NEW |
| TENET HEALTHCARE CORP | 92500 | 18381600 | COM NEW |
| ARCUS BIOSCIENCES INC | 711983 | 16966555 | COM |
| ENLIVEN THERAPEUTICS INC | 1025000 | 15785000 | COM |
| MBX BIOSCIENCES INC | 408900 | 12896706 | COM |
| RIGEL PHARMACEUTICALS INC | 300034 | 12850456 | COM |
| JADE BIOSCIENCES INC | 796744 | 12293760 | COM NEW |
| TREVI THERAPEUTICS INC | 900000 | 11268000 | COM |
| SIONNA THERAPEUTICS INC | 268500 | 11046090 | COM |
| SEPTERNA INC | 383368 | 10688300 | COM |
| ORTHOPEDIATRICS CORP | 525447 | 9331939 | COM |
| TERNS PHARMACEUTICALS INC | 212710 | 8593484 | COM |
| CIDARA THERAPEUTICS INC | 38811 | 8572962 | COM NEW |
| INSMED INC | 48500 | 8440940 | COM PAR $.01 |
| CERUS CORP | 4000000 | 8240000 | COM |
| ERASCA INC | 2162162 | 8043243 | COM |
| AVALO THERAPEUTICS INC | 441978 | 8026320 | COM NEW |
| C4 THERAPEUTICS INC | 3803942 | 7265529 | COM STK |
| EVOLUS INC | 1070000 | 7115500 | COM |
| CG ONCOLOGY INC | 170000 | 7058400 | COM |
| ANAPTYSBIO INC | 135000 | 6544800 | COM |
| BELITE BIO INC | 40354 | 6455026 | SPONSORED ADS |
| STRUCTURE THERAPEUTICS INC | 90000 | 6259500 | SPONSORED ADS |
| ABIVAX SA | 45000 | 6068475 | SPONSORED ADS |
| ORUKA THERAPEUTICS INC | 190000 | 5758900 | COM |
| MOONLAKE IMMUNOTHERAPEUTICS | 400000 | 5272000 | CLASS A ORD |
| NEOGENOMICS INC | 427504 | 5027447 | COM NEW |
| NATERA INC | 20000 | 4581800 | COM |
| CALCIMEDICA INC | 683904 | 4506927 | COM NEW |
| PULMONX CORP | 2038323 | 4504694 | COM |
| COGENT BIOSCIENCES INC | 120000 | 4262400 | COM |
| INDIVIOR PLC | 100000 | 3588000 | ORD |
| UROGEN PHARMA LTD | 150000 | 3513000 | COM |
| TYRA BIOSCIENCES INC | 125000 | 3286250 | COM |
| KARYOPHARM THERAPEUTICS INC | 440000 | 3238400 | COM NEW |
| ZYMEWORKS INC | 100000 | 2633000 | COM |
| VIKING THERAPEUTICS INC | 70000 | 2462600 | COM |
| QUIDELORTHO CORP | 75000 | 2142000 | COM |
| INSPIREMD INC | 1150000 | 2047000 | COM |
| INHIBRX BIOSCIENCES INC | 25000 | 1975000 | COM |
| ARCELLX INC | 30000 | 1956000 | COMMON STOCK |
| OLEMA PHARMACEUTICALS INC | 69874 | 1746850 | COM |
| BICARA THERAPEUTICS INC | 100000 | 1683000 | COM |
| KODIAK SCIENCES INC | 60000 | 1677600 | COM |
| GRAIL INC | 11000 | 941490 | COM |
| FRACTYL HEALTH INC | 400000 | 880000 | COM |
| STAAR SURGICAL CO | 25000 | 577250 | COM PAR $0.01 |
| VERACYTE INC | 10000 | 421000 | COM |
| JASPER THERAPEUTICS INC | 200000 | 366000 | COM NEW |
| QUOIN PHARMACEUTICALS LTD | 25000 | 360750 | SPONSORED ADS |
| MADRIGAL PHARMACEUTICALS INC | 500 | 291170 | COM |
| LB PHARMACEUTICALS INC | 10000 | 222600 | COM SHS |
| DYNE THERAPEUTICS INC | 10000 | 195600 | COM |
| DELCATH SYS INC | 10000 | 101000 | COM NEW |
| TANGO THERAPEUTICS INC | 10000 | 88600 | COM |
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