Sofinnova Investments, Inc. - Stock Holdings in 13F Filings (SEC)
Updated on March 15, 2026.
Based on 13F Filings filed with the SEC on February 13, 2026, for the 2025 Q4 period, Sofinnova Investments, Inc. held in its portfolio 60 assets valued at $2,319,284,145 (i.e. $2.32B).
The most valuable assets in the portfolio included: NATERA INC ($355.15M), JAZZ PHARMACEUTICALS PLC ($163.18M), and ASTRAZENECA PLC ($150.06M).
The chart below shows the top 10 valuable assets, and the table below shows the top 60 valuable assets.
You can see similar for other investment managers.
Related Topics: SEC Topic List.
Data Source: SEC.
Sofinnova Investments, Inc. - Stock Holdings in 13F Filings (SEC)
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| Name of Issuer | No. of Shares | Value ($) | Class |
|---|---|---|---|
| NATERA INC | 1550280 | 355153645 | COM |
| JAZZ PHARMACEUTICALS PLC | 959860 | 163176200 | SHS USD |
| ASTRAZENECA PLC | 1632334 | 150060465 | SPONSORED ADR |
| VERA THERAPEUTICS INC | 2793987 | 141487502 | CL A |
| BRISTOL-MYERS SQUIBB CO | 1512994 | 81610896 | COM |
| UNITED THERAPEUTICS CORP | 157641 | 76810577 | COM |
| VERTEX PHARMACEUTICALS INC | 164594 | 74620336 | COM |
| ABBVIE INC | 317783 | 72610238 | COM |
| INTUITIVE SURGICAL INC | 126968 | 71909596 | COM |
| COGENT BIOSCIENCES INC | 1973625 | 70103160 | COM |
| ELI LILLY & CO | 61652 | 66256171 | COM |
| RAPPORT THERAPEUTICS INC | 1904408 | 57779739 | COM |
| BRIDGEBIO PHARMA INC | 720448 | 55107068 | COM |
| AVIDITY BIOSCIENCES INC | 745116 | 53745217 | COM |
| DYNE THERAPEUTICS INC | 2254161 | 44091389 | COM |
| BIOMARIN PHARMACEUTICAL INC | 697133 | 41430614 | COM |
| APOGEE THERAPEUTICS INC | 534845 | 40370101 | COM |
| CIDARA THERAPEUTICS INC | 180265 | 39818736 | COM |
| PRAXIS PRECISION MEDICINES INC | 125722 | 37055302 | COM |
| IMMATICS N.V | 3435542 | 36073191 | SHS |
| INHIBRX BIOSCIENCES INC | 454657 | 35917903 | COM |
| IMMUNOME INC | 1618477 | 34764886 | COM |
| ARRIVENT BIOPHARMA INC | 1696752 | 34138650 | COM |
| GLAUKOS CORP | 288128 | 32532532 | COM |
| IDEAYA BIOSCIENCES INC | 885121 | 30598633 | COM |
| BIOAGE LABS INC | 2293788 | 30346815 | COM |
| CELCUITY INC | 299417 | 29863852 | COM |
| RHYTHM PHARMACEUTICALS INC | 271394 | 29050014 | COM |
| CENTESSA PHARMACEUTICALS PLC | 1104274 | 27617893 | SPONSORED ADS |
| SUPERNUS PHARMACEUTICALS INC | 553095 | 27488822 | COM |
| INSMED INC | 156801 | 27289646 | COM PAR $.01 |
| ALCON AG | 332520 | 26205901 | ORD SHS |
| ARCUS BIOSCIENCES INC | 1096705 | 26134480 | COM |
| DEXCOM INC | 378219 | 25102395 | COM |
| PHARVARIS N V | 745169 | 20678440 | COM |
| NEKTAR THERAPEUTICS | 438630 | 18545276 | COM |
| COMPASS THERAPEUTICS INC | 3365446 | 18072445 | COM |
| ROIVANT SCIENCES LTD | 734582 | 15940429 | SHS |
| ANAPTYSBIO INC | 287690 | 13947211 | COM |
| GE HEALTHCARE TECHNOLOGIES I | 160876 | 13195050 | COMMON STOCK |
| EDGEWISE THERAPEUTICS INC | 437819 | 10864478 | COM |
| EXACT SCIENCES CORP | 101443 | 10302551 | COM |
| DISC MEDICINE INC | 111010 | 8815304 | COM |
| AMYLYX PHARMACEUTICALS INC | 527099 | 6367356 | COM |
| MASIMO CORP | 46201 | 6008902 | COM |
| UNIQURE NV | 176513 | 4223956 | SHS |
| NEXTCURE INC | 222654 | 3159460 | COM |
| WAVE LIFE SCIENCES LTD | 158182 | 2689094 | SHS |
| XENON PHARMACEUTICALS INC | 59900 | 2684718 | COM |
| EVOMMUNE INC | 153320 | 2624838 | COM SHS |
| AXSOME THERAPEUTICS INC | 12266 | 2240262 | COM |
| ESTABLISHMENT LABS HLDGS INC | 28366 | 2067314 | COM |
| ULTRAGENYX PHARMACEUTICAL INC | 83300 | 1915900 | COM |
| SAVARA INC | 304770 | 1837763 | COM |
| MIRUM PHARMACEUTICALS INC | 23100 | 1824669 | COM |
| ACADIA PHARMACEUTICALS INC | 65567 | 1751295 | COM |
| JADE BIOSCIENCES INC | 107391 | 1657043 | COM |
| BOLT BIOTHERAPEUTICS INC | 137721 | 753058 | COM |
| SOLENO THERAPEUTICS INC | 12414 | 574768 | COM |
| IMAGENEBIO INC | 31884 | 220000 | COM |
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