PERCEPTIVE ADVISORS LLC - Stock Holdings in 13F Filings (SEC)
Updated on March 15, 2026.
Based on 13F Filings filed with the SEC on February 17, 2026, for the 2025 Q4 period, PERCEPTIVE ADVISORS LLC held in its portfolio 115 assets valued at $5,610,284,266 (i.e. $5.61B).
The most valuable assets in the portfolio included: PRAXIS PRECISION MEDICINES I ($588.30M), CELCUITY INC ($315.20M), and RHYTHM PHARMACEUTICALS INC ($272.57M).
The chart below shows the top 10 valuable assets, and the table below shows the top 115 valuable assets.
You can see similar for other investment managers.
Related Topics: SEC Topic List.
Data Source: SEC.
PERCEPTIVE ADVISORS LLC - Stock Holdings in 13F Filings (SEC)
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| Name of Issuer | No. of Shares | Value ($) | Class |
|---|---|---|---|
| PRAXIS PRECISION MEDICINES I | 1995986 | 588296914 | COM NEW |
| CELCUITY INC | 3160200 | 315198348 | COM |
| RHYTHM PHARMACEUTICALS INC | 2546391 | 272565693 | COM |
| ASCENDIS PHARMA A/S | 1081421 | 230602214 | SPONSORED ADR |
| APOGEE THERAPEUTICS INC | 2330651 | 175917537 | COM |
| ROIVANT SCIENCES LTD | 7985461 | 173284504 | SHS |
| NUVALENT INC | 1665105 | 167492912 | COM |
| TRAVERE THERAPEUTICS INC | 4278180 | 163469258 | COM |
| SPDR SERIES TRUST | 1100000 | 134123000 | STATE STREET SPD |
| EXACT SCIENCES CORP | 1200487 | 121921460 | COM |
| PROTAGONIST THERAPEUTICS INC | 1350425 | 117946120 | COM |
| INHIBRX BIOSCIENCES INC | 1452707 | 114763853 | COM |
| EDGEWISE THERAPEUTICS | 4457974 | 110624625 | COM |
| IMMATICS N.V | 10383456 | 109026288 | SHS |
| SPYRE THERAPEUTICS INC | 3069225 | 100547811 | COM NEW |
| AMYLYX PHARMACEUTICALS INC | 8284882 | 100081375 | COM |
| ARCELLX INC | 1466071 | 95587829 | COMMON STOCK |
| VIRIDIAN THERAPEUTICS INC | 3042703 | 94688917 | COM |
| BOSTON SCIENTIFIC CORP | 979000 | 93347650 | COM |
| AMICUS THERAPEUTICS INC | 6370851 | 90720918 | COM |
| ZYMEWORKS INC | 3261850 | 85884511 | COM |
| ASTRIA THERAPEUTICS INC | 6485420 | 84894147 | COM |
| MEIRAGTX HLDGS PLC | 10326103 | 82092519 | COM |
| ARTIVION INC | 1722290 | 78553647 | COM |
| CENTESSA PHARMACEUTICALS PLC | 2917634 | 72970026 | SPONSORED ADS |
| DYNE THERAPEUTICS INC | 3478944 | 68048145 | COM |
| NURIX THERAPEUTICS INC | 3555877 | 67454987 | COM |
| SOLID BIOSCIENCES INC | 11833539 | 66741160 | COM NEW |
| BELITE BIO INC | 414239 | 66261670 | SPONSORED ADS |
| ABIVAX SA | 458343 | 61809845 | SPONSORED ADS |
| INVIVYD INC | 21785166 | 53809360 | COM |
| ENGENE HOLDINGS INC | 5869076 | 52997756 | COM |
| REPLIGEN CORP | 315541 | 51704548 | COM |
| IMMUNOVANT INC | 1994890 | 50710104 | COM |
| INTUITIVE SURGICAL INC | 87919 | 49793805 | COM NEW |
| SIONNA THERAPEUTICS INC | 1179098 | 48508092 | COM |
| NEUROCRINE BIOSCIENCES INC | 331050 | 46952821 | COM |
| DANAHER CORPORATION | 200000 | 45784000 | COM |
| ORUKA THERAPEUTICS INC | 1476501 | 44752745 | COM |
| CYTOMX THERAPEUTICS INC | 9680185 | 41237588 | COM |
| OMADA HEALTH INC | 2396330 | 37814087 | COM |
| CIDARA THERAPEUTICS INC | 165131 | 36475787 | COM NEW |
| DISC MEDICINE INC | 450743 | 35793502 | COM |
| BRIGHT MINDS BIOSCIENCES INC | 449290 | 35062592 | COM NEW |
| PENUMBRA INC | 110529 | 34364571 | COM |
| ALTO NEUROSCIENCE INC | 1784393 | 31762195 | COM SHS |
| CARIS LIFE SCIENCES INC | 1136206 | 30654838 | COM |
| JAZZ PHARMACEUTICALS PLC | 170000 | 28900000 | SHS USD |
| PALISADE BIO INC | 12050000 | 28317500 | COM |
| RAPT THERAPEUTICS INC | 825890 | 27972894 | COM NEW |
| PALVELLA THERAPEUTICS INC NE | 266287 | 27872260 | COM |
| AXSOME THERAPEUTICS INC | 148900 | 27195096 | COM |
| AXOGEN INC | 784140 | 25664902 | COM |
| X4 PHARMACEUTICALS INC | 6314452 | 25257808 | COM NEW |
| BIOCRYST PHARMACEUTICALS INC | 3162529 | 24667726 | COM |
| NAUTILUS BIOTECHNOLOGY INC | 12594211 | 24558711 | COM |
| KODIAK SCIENCES INC | 848900 | 23735244 | COM |
| BIOGEN INC | 124000 | 21822760 | COM |
| ALDEYRA THERAPEUTICS INC | 4185632 | 21681574 | COM |
| ORCHESTRA BIOMED HLDGS INC | 5127256 | 21278112 | COM |
| MIRUM PHARMACEUTICALS INC | 259545 | 20501460 | COM |
| RAPPORT THERAPEUTICS INC | 673923 | 20446824 | COM |
| GRAIL INC | 237342 | 20314102 | COM |
| IRHYTHM TECHNOLOGIES INC | 108000 | 19163520 | COM |
| BETA BIONICS INC | 602944 | 18371704 | COM |
| CVS HEALTH CORP | 220000 | 17459200 | COM |
| CONTINEUM THERAPEUTICS INC | 1464592 | 16740287 | CL A |
| GUARDANT HEALTH INC | 160000 | 16342400 | COM |
| ADMA BIOLOGICS INC | 883468 | 16114456 | COM |
| RELAY THERAPEUTICS INC | 1903245 | 16101453 | COM |
| GLAUKOS CORP | 140000 | 15807400 | COM |
| DEXCOM INC | 225758 | 14983558 | COM |
| SAVARA INC | 2400000 | 14472000 | COM |
| ATHIRA PHARMA INC | 1859322 | 14075067 | COM |
| SEPTERNA INC | 433160 | 12076501 | COM |
| INHIBIKASE THERAPEUTICS INC | 5421568 | 11114214 | COM NEW |
| ADAGIO MED HLDGS INC | 9876576 | 10271639 | COM |
| OCULIS HOLDING AG | 493827 | 9861725 | ORDINARY SHARES |
| GOSSAMER BIO INC | 3139669 | 9732974 | COM |
| MAPLIGHT THERAPEUTICS INC | 550000 | 9660750 | COM |
| XENON PHARMACEUTICALS INC | 200791 | 8999453 | COM |
| OPUS GENETICS INC | 4325000 | 8693250 | COM |
| ANTERIS TECHNOLOGIES GLOBAL | 1675476 | 8360625 | COM |
| KESTRA MED TECHNOLOGIES LTD | 285000 | 7558200 | SHS |
| CAPRICOR THERAPEUTICS INC | 242100 | 6987006 | COM NEW |
| BILLIONTOONE INC | 72812 | 5958934 | CL A |
| BIOHAVEN LTD | 500000 | 5645000 | COM |
| KYMERA THERAPEUTICS INC | 69935 | 5441642 | COM |
| PEPGEN INC | 829870 | 5402454 | COM |
| CRESCENT BIOPHARMA INC. | 453686 | 5380716 | COM |
| TENAX THERAPEUTICS INC | 439142 | 5353141 | COM NEW |
| CORVUS PHARMACEUTICALS INC | 692441 | 5331796 | COM |
| TECTONIC THERAPEUTIC INC | 250000 | 5215000 | COM |
| AQUESTIVE THERAPEUTICS INC | 747193 | 4826867 | COM |
| TANGO THERAPEUTICS INC | 513035 | 4545490 | COM |
| KRYSTAL BIOTECH INC | 17500 | 4314450 | COM |
| COGENT BIOSCIENCES INC | 121082 | 4300833 | COM |
| OLEMA PHARMACEUTICALS INC | 165713 | 4142825 | COM |
| SCHRODINGER INC | 202400 | 3618912 | COM |
| OUTSET MED INC | 833333 | 3091665 | COM NEW |
| SAB BIOTHERAPEUTICS INC | 803210 | 3004005 | COM NEW |
| AVALO THERAPEUTICS INC | 139667 | 2536353 | COM NEW |
| CONNECT BIOPHARMA HLDGS LTD | 792696 | 2235403 | SHS |
| IMMIX BIOPHARMA INC | 338941 | 1772661 | COM |
| LEXEO THERAPEUTICS INC | 139835 | 1388562 | COM |
| CUMBERLAND PHARMACEUTICALS I | 341087 | 1357526 | COM |
| MEDLINE INC | 28000 | 1176000 | COM CL A |
| PALATIN TECHNOLOGIES INC | 70000 | 1076600 | COM NEW |
| LENZ THERAPEUTICS INC | 50000 | 800000 | COM |
| BIODESIX | 108694 | 739119 | COM |
| ENVVENO MEDICAL CORPORATION | 1759035 | 564298 | COM |
| IOVANCE BIOTHERAPEUTICS INC | 152714 | 416909 | COM |
| REVOLUTION MEDICINES INC | 250000 | 234975 | *W EXP 12/17/202 |
| ENSYSCE BIOSCIENCES INC | 86666 | 79733 | COM NEW |
| SURROZEN INC | 166666 | 3333 | *W EXP 08/01/203 |
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