Paradigm Biocapital Advisors LP - Stock Holdings in 13F Filings (SEC)
Updated on March 15, 2026.
Based on 13F Filings filed with the SEC on February 17, 2026, for the 2025 Q4 period, Paradigm Biocapital Advisors LP held in its portfolio 30 assets valued at $3,917,829,903 (i.e. $3.92B).
The most valuable assets in the portfolio included: NUVALENT INC ($530.05M), REVOLUTION MEDICINES INC ($529.23M), and ARCELLX INC ($373.21M).
The chart below shows the top 10 valuable assets, and the table below shows the top 30 valuable assets.
You can see similar for other investment managers.
Related Topics: SEC Topic List.
Data Source: SEC.
Paradigm Biocapital Advisors LP - Stock Holdings in 13F Filings (SEC)
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| Name of Issuer | No. of Shares | Value ($) | Class |
|---|---|---|---|
| NUVALENT INC | 5269433 | 530052265 | COM |
| REVOLUTION MEDICINES INC | 6644403 | 529226699 | COM |
| ARCELLX INC | 5724016 | 373205843 | COMMON STOCK |
| GENMAB A/S | 7039834 | 216826887 | SPONSORED ADS |
| TARSUS PHARMACEUTICALS INC | 2562154 | 209789170 | COM |
| ABIVAX SA | 1417473 | 191153321 | SPONSORED ADS |
| OLEMA PHARMACEUTICALS INC | 7544172 | 188604300 | COM |
| VAXCYTE INC | 4068020 | 187698443 | COM |
| SPDR SERIES TRUST | 1500000 | 182895000 | STATE STREET SPD |
| CIDARA THERAPEUTICS INC | 759565 | 167780313 | COM NEW |
| EDGEWISE THERAPEUTICS INC | 6541210 | 162320126 | COM |
| SCHOLAR ROCK HLDG CORP | 3062157 | 134888016 | COM |
| UROGEN PHARMA LTD | 4473648 | 104772836 | COM |
| CRINETICS PHARMACEUTICALS IN | 2210774 | 102911530 | COM |
| APOGEE THERAPEUTICS INC | 1123243 | 84782382 | COM |
| EYEPOINT INC | 3691475 | 67443248 | COM NEW |
| ERASCA INC | 14159095 | 52671833 | COM |
| BRIDGEBIO PHARMA INC | 684277 | 52340348 | COM |
| ORUKA THERAPEUTICS INC | 1710316 | 51839678 | COM |
| SPYRE THERAPEUTICS INC | 1467266 | 48067634 | COM NEW |
| LEXEO THERAPEUTICS INC | 4763198 | 47298556 | COM |
| VIRIDIAN THERAPEUTICS INC | 1443102 | 44909334 | COM |
| OCULAR THERAPEUTIX INC | 2935284 | 35634348 | COM |
| TERNS PHARMACEUTICALS INC | 810286 | 32735554 | COM |
| BRIDGEBIO ONCOLOGY THERAPEUT | 2261749 | 28317097 | COM NEW |
| VOR BIOPHARMA INC | 1750000 | 22890000 | COM NEW |
| ASSEMBLY BIOSCIENCES INC | 665251 | 22625187 | COM NEW |
| ORIC PHARMACEUTICALS INC | 2401217 | 19641955 | COM |
| INVENTIVA SA | 4000000 | 18600000 | ADS |
| KALARIS THERAPEUTICS INC | 700000 | 5908000 | COM |
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