Opaleye Management Inc. - Stock Holdings in 13F Filings (SEC)
Updated on March 15, 2026.
Based on 13F Filings filed with the SEC on February 17, 2026, for the 2025 Q4 period, Opaleye Management Inc. held in its portfolio 54 assets valued at $757,989,521 (i.e. $757.99M).
The most valuable assets in the portfolio included: HARROW HEALTH INC ($191.35M), LIQUIDIA CORPORATION ($84.98M), and ETON PHARMACEUTICALS INC ($48.36M).
The chart below shows the top 10 valuable assets, and the table below shows the top 54 valuable assets.
You can see similar for other investment managers.
Related Topics: SEC Topic List.
Data Source: SEC.
Opaleye Management Inc. - Stock Holdings in 13F Filings (SEC)
Items per page:
25
0 of 0
| Name of Issuer | No. of Shares | Value ($) | Class |
|---|---|---|---|
| HARROW HEALTH INC | 3905000 | 191345000 | COM |
| LIQUIDIA CORPORATION | 2435000 | 84981500 | COM NEW |
| ETON PHARMACEUTICALS INC | 2860000 | 48362600 | COM |
| RHYTHM PHARMACEUTICALS INC | 330000 | 35323200 | COM |
| APOGEE THERAPEUTICS INC | 388257 | 29305638 | COM |
| SANUWAVE HEALTH INC | 981267 | 29281007 | COM |
| STOKE THERAPEUTICS INC | 695000 | 22059300 | COM |
| OCULAR THERAPEUTIX INC | 1595000 | 19363300 | COM |
| SOL GEL TECHNOLOGIES | 453739 | 19120561 | SHS NEW |
| CG ONCOLOGY INC | 410000 | 17023200 | COM |
| TG THERAPEUTICS INC | 535000 | 15948350 | COM |
| DISC MEDICINE INC | 200000 | 15882000 | COM |
| REZOLUTE INC | 6287156 | 14837688 | COM NEW |
| CRESCENT BIOPHARMA INC | 1178300 | 13974638 | COM |
| ALKERMES PLC | 490000 | 13710200 | SHS |
| ALPHA COGNITION INC | 2070784 | 13460096 | COM NEW |
| ANNEXON INC | 2600000 | 13052000 | COM |
| EDGEWISE THERAPEUTICS INC | 500000 | 12407500 | COM |
| CODEXIS INC | 6789738 | 11067273 | COM |
| PROTAGONIST THERAPEUTICS INC | 105000 | 9170700 | COM |
| GOSSAMER BIO INC | 2720000 | 8432000 | COM |
| MBX BIOSCIENCES INC | 260000 | 8200400 | COM |
| REVOLUTION MEDICINES INC | 100000 | 7965000 | COM |
| XOMA CORP DEL | 292590 | 7779968 | COM NEW |
| JOURNEY MEDICAL CORP | 975000 | 7517250 | COM |
| KARYOPHARM THERAPEUTICS INC | 930000 | 6844800 | COM NEW |
| JADE BIOSCIENCES INC | 427608 | 6597991 | COM NEW |
| UROGEN PHARMA LTD | 268423 | 6286467 | COM |
| ALUMIS INC | 535000 | 5221600 | COM |
| PERSPECTIVE THERAPEUTICS INC | 1184500 | 4989875 | COM |
| VOYAGER THERAPEUTICS INC | 1196904 | 4703833 | COM |
| RELMADA THERAPEUTICS INC | 935000 | 4516050 | COM |
| TECTONIC THERAPEUTICS INC | 214747 | 4479622 | COM |
| PROTALIX BIOTHERAPEUTICS INC | 2478176 | 4460717 | COM |
| TREVI THERAPEUTICS INC | 345100 | 4320652 | COM |
| FORTRESS BIOTECH INC | 1090000 | 3989400 | COM NEW |
| ROCKET PHARMACEUTICALS INC | 955000 | 3352050 | COM |
| MEIRAGTX HOLDINGS PLC | 390844 | 3107210 | COM |
| RIGEL PHARMACEUTICALS INC | 70000 | 2998100 | COM |
| ZYMEWORKS INC | 108929 | 2868101 | COM |
| ASSERTIO HOLDINGS INC | 285000 | 2584950 | COM NEW |
| VENTYX BIOSCIENCES INC | 251932 | 2274946 | COM |
| OPUS GENETICS INC | 1120000 | 2251200 | COM |
| SUTRO BIOPHARMA INC | 190671 | 2206063 | COM SHS |
| CABALETTA BIO INC | 900000 | 1971000 | COM |
| ZENTALIS PHARMACEUTICALS INC | 1400906 | 1891223 | COM |
| GENERATION BIO CO | 310000 | 1760800 | COM NEW |
| BRIDGEBIO PHARMA INC | 18319 | 1401220 | COM |
| ENANTA PHARMACEUTICALS INC | 75000 | 1182750 | COM |
| Q32 BIO INC | 213363 | 708365 | COM |
| ATEA PHARMACEUTICALS INC | 179815 | 641940 | COM |
| SILENCE THERAPEUTICS PLC | 78926 | 479870 | ADS |
| RAPT THERAPEUTICS INC | 150000 | 213363 | COM NEW |
| ADAGIO MED HLDGS INC | 110571 | 114994 | COM |
Popular Topics:
Find us
Copyright © Beautify Data LLC. All Rights Reserved.