EcoR1 Capital, LLC - Stock Holdings in 13F Filings (SEC)
Updated on March 15, 2026.
Based on 13F Filings filed with the SEC on February 17, 2026, for the 2025 Q4 period, EcoR1 Capital, LLC held in its portfolio 28 assets valued at $2,204,008,593 (i.e. $2.20B).
The most valuable assets in the portfolio included: ZYMEWORKS INC ($604.81M), ANAPTYSBIO INC ($382.03M), and JAZZ PHARMACEUTICALS PLC ($290.10M).
The chart below shows the top 10 valuable assets, and the table below shows the top 28 valuable assets.
You can see similar for other investment managers.
Related Topics: SEC Topic List.
Data Source: SEC.
EcoR1 Capital, LLC - Stock Holdings in 13F Filings (SEC)
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| Name of Issuer | No. of Shares | Value ($) | Class |
|---|---|---|---|
| ZYMEWORKS INC | 22970388 | 604810316 | COM |
| ANAPTYSBIO INC | 7880094 | 382026957 | COM |
| JAZZ PHARMACEUTICALS PLC | 1706469 | 290099730 | SHS USD |
| CRINETICS PHARMACEUTICALS IN | 4288120 | 199611986 | COM |
| CENTESSA PHARMACEUTICALS PLC | 3115000 | 77906150 | SPONSORED ADS |
| CRISPR THERAPEUTICS AG | 1389276 | 72853633 | NAMEN AKT |
| MBX BIOSCIENCES INC | 2123604 | 66978470 | COM |
| IMMUNOME INC | 2855590 | 61338073 | COM |
| ORIC PHARMACEUTICALS INC | 6728116 | 55035989 | COM |
| GALAPAGOS NV | 1667119 | 54514791 | SPON ADR |
| XENCOR INC | 3318612 | 50807950 | COM |
| CG ONCOLOGY INC | 1064800 | 44210496 | COM |
| BRIDGEBIO ONCOLOGY THERAPEUT | 2823126 | 35345538 | COM NEW |
| ETON PHARMACEUTICALS INC | 2030544 | 34336499 | COM |
| ZENAS BIOPHARMA INC | 789500 | 28666745 | COM |
| NEUROGENE INC | 1271342 | 26189645 | COM |
| STRUCTURE THERAPEUTICS INC | 334380 | 23256129 | SPONSORED ADS |
| VAXCYTE INC | 450000 | 20763000 | COM |
| AQUESTIVE THERAPEUTICS INC | 2625000 | 16957500 | COM |
| VOYAGER THERAPEUTICS INC | 4002847 | 15731189 | COM |
| ATARA BIOTHERAPEUTICS INC | 573183 | 10368880 | COM NEW |
| MANNKIND CORP | 1660000 | 9412200 | COM NEW |
| NUVATION BIO INC | 963333 | 8631464 | *W EXP 02/10/202 |
| EVOLUS INC | 675000 | 4488750 | COM |
| IBIO INC | 2228000 | 4300040 | COM NEW |
| MEREO BIOPHARMA GROUP PLC | 7856466 | 3273789 | SPON ADS |
| CAMP4 THERAPEUTICS CORP | 325000 | 1992250 | COM |
| SURROZEN INC | 4444 | 100434 | *W EXP 08/01/203 |