DAFNA Capital Management LLC - Stock Holdings in 13F Filings (SEC)
Updated on March 15, 2026.
Based on 13F Filings filed with the SEC on February 17, 2026, for the 2025 Q4 period, DAFNA Capital Management LLC held in its portfolio 76 assets valued at $430,518,714 (i.e. $430.52M).
The most valuable assets in the portfolio included: REVOLUTION MEDICINES INC ($48.15M), SPDR S&P BIOTECH ETF ($41.03M), and STEREOTAXIS INC ($31.47M).
The chart below shows the top 10 valuable assets, and the table below shows the top 76 valuable assets.
You can see similar for other investment managers.
Related Topics: SEC Topic List.
Data Source: SEC.
DAFNA Capital Management LLC - Stock Holdings in 13F Filings (SEC)
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| Name of Issuer | No. of Shares | Value ($) | Class |
|---|---|---|---|
| REVOLUTION MEDICINES INC | 604514 | 48149540 | COM |
| SPDR S&P BIOTECH ETF | 336505 | 41030055 | ETF |
| STEREOTAXIS INC | 13680554 | 31465274 | COM NEW |
| ATRICURE INC | 597431 | 23634370 | COM |
| CYTOKINETICS INC | 370997 | 23573149 | COM NEW |
| IDEAYA BIOSCIENCES INC | 506740 | 17518002 | COM |
| AXOGEN INC | 476826 | 15606515 | COM |
| XENON PHARMACEUTICALS INC | 287939 | 12905426 | COM |
| ISHARES NASDAQ BIOTECH INDX | 68095 | 11492393 | ETF |
| BIOHAVEN LTD | 955235 | 10784603 | COM |
| ARCUS BIOSCIENCES INC | 431329 | 10278570 | COM |
| NEUROCRINE BIOSCIENCES INC | 70615 | 10015325 | COM |
| DAY ONE BIOPHARMACEUTICALS I | 999163 | 9312199 | COM |
| TANDEM DIABETES CARE INC | 355208 | 7807472 | COM NEW |
| ASCENDIS PHARMA A/S | 28177 | 6008463 | SPONSORED ADR |
| DEXCOM INC | 88279 | 5859077 | COM |
| SYNDAX PHARMACEUTICALS INC | 277855 | 5837734 | COM |
| KALVISTA PHARMACEUTICALS INC | 356802 | 5762352 | COM |
| COMPASS PATHWAYS PLC | 811046 | 5596217 | SPONSORED ADS |
| INOGEN INC | 827071 | 5557917 | COM |
| DENALI THERAPEUTICS INC | 318500 | 5258435 | COM |
| MBX BIOSCIENCES INC | 165265 | 5212458 | COM |
| BICARA THERAPEUTICS INC | 261583 | 4402442 | COM |
| GALAPAGOS NV | 130175 | 4256723 | SPON ADR |
| ASTRIA THERAPEUTICS INC | 304775 | 3989505 | COM |
| EDGEWISE THERAPEUTICS INC | 159736 | 3963849 | COM |
| IMMUNOVANT INC | 150524 | 3826320 | COM |
| PROCEPT BIOROBOTICS CORP | 120000 | 3775200 | COM |
| CYBIN INC | 455018 | 3722047 | COM NEW |
| ALKERMES PLC | 130248 | 3644339 | SHS |
| LARIMAR THERAPEUTICS INC | 939164 | 3578215 | COM |
| STOKE THERAPEUTICS INC | 108875 | 3455693 | COM |
| LEXEO THERAPEUTICS INC | 340859 | 3384730 | COM |
| BIOCRYST PHARMACEUTICALS INC | 418255 | 3262389 | COM |
| NEKTAR THERAPEUTICS | 74998 | 3170915 | COM NEW |
| PROQR THERAPEUTICS N V | 1567561 | 3166473 | SHS EURO |
| CENTURY THERAPEUTICS INC | 2793586 | 2779059 | COM |
| IMMATICS NV | 261138 | 2741949 | SHS |
| STRUCTURE THERAPEUTICS INC | 37000 | 2573350 | SPONSORED ADS |
| MAPLIGHT THERAPEUTICS INC | 143764 | 2525215 | COM |
| ALIGN TECHNOLOGY INC | 16000 | 2498400 | COM |
| KURA ONCOLOGY INC | 235868 | 2450669 | COM |
| AQUESTIVE THERAPEUTICS INC | 375915 | 2428411 | COM |
| RAPPORT THERAPEUTICS INC | 75000 | 2275500 | COM |
| PROFOUND MEDICAL CORP | 285710 | 2248538 | COM NEW |
| ARS PHARMACEUTICALS INC | 190065 | 2214257 | COM |
| MEDIWOUND LTD | 113612 | 2097278 | SHS NEW |
| VIKING THERAPEUTICS INC | 59516 | 2093773 | COM |
| INSULET CORP | 6870 | 1952729 | COM |
| ALLOGENE THERAPEUTICS INC | 1380118 | 1890762 | COM |
| CELLDEX THERAPEUTICS INC NEW | 68518 | 1860949 | COM NEW |
| TELA BIO INC | 1441029 | 1700414 | COM |
| ENGENE HOLDINGS INC | 163645 | 1477714 | COM |
| VERRICA PHARMACEUTICALS INC | 173451 | 1441378 | COM SHS |
| ALECTOR INC | 908351 | 1417028 | COM |
| MINERALYS THERAPEUTICS INC | 38490 | 1396802 | COM |
| ANNEXON INC | 272812 | 1369516 | COM |
| ORIC PHARMACEUTICALS INC | 141045 | 1153748 | COM |
| ACCURAY INC | 1395508 | 1150736 | COM |
| ERASCA INC | 254436 | 946502 | COM |
| POLYPID LTD | 207900 | 902286 | COM |
| INSPIRE MEDICAL SYSTEMS INC | 8600 | 793178 | COM |
| ADICET BIO INC | 93812 | 789897 | COM NEW |
| FOGHORN THERAPEUTICS INC | 126859 | 685039 | COM |
| BIONTECH SE | 7000 | 666400 | SPONSORED ADS |
| NEUROGENE INC | 27974 | 576264 | COM |
| FATE THERAPEUTICS INC | 550000 | 540430 | COM |
| ORCHESTRA BIOMED HOLDINGS INC | 126841 | 526390 | COM |
| BICYCLE THERAPEUTICS PLC | 64492 | 456603 | SPONSORED ADS |
| COMPUGEN LTD | 272402 | 416775 | ORD |
| KARYOPHARM THERAPEUTICS | 51000 | 375360 | COM NEW |
| ULTRAGENYX PHARMACEUTICAL INC | 16000 | 368000 | COM |
| AUTOLUS THERAPEUTICS PLC | 179316 | 356839 | SPON ADS |
| ADC THERAPEUTICS SA | 77081 | 272096 | SHS |
| BRAINSWAY LTD | 12965 | 246594 | SPONSORED ADS |
| PERSPECTIVE THERAPEUTICS INC | 50000 | 137500 | COM NEW |
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