South Carolina Population By County in 2021 (ACS-5Yrs)

Updated on February 28, 2025.

Based on the US Census ACS-5Yrs estimates, in 2021, the total population of South Carolina was 5.08M. Among all South Carolina counties, Greenville was the most populated county (519.18K), followed by Richland (414.72K), and then Charleston (404.95K).

On the other hand, the least populated counties were: Allendale (8.30K), McCormick (9.58K), and Bamberg (13.53K).

The chart and table below shows the population of each county and the percentage of South Carolina population in each county.

You can see similar information for other states and by state for the United States.

Related Topics: South Carolina ACS-5Yrs Estimates, 2021 Topic List.

Data Source: US Census - ACS 5-Year Estimates, 2021 Census.

South Carolina Population By County in 2021

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County	Population	% of State Population
Abbeville	24374	0.48
Aiken	168045	3.31
Allendale	8304	0.16
Anderson	202223	3.98
Bamberg	13525	0.27
Barnwell	20801	0.41
Beaufort	186007	3.66
Berkeley	224806	4.43
Calhoun	14198	0.28
Charleston	404946	7.97
Cherokee	56204	1.11
Chester	32273	0.64
Chesterfield	43655	0.86
Clarendon	31613	0.62
Colleton	38520	0.76
Darlington	63433	1.25
Dillon	28527	0.56
Dorchester	160180	3.15
Edgefield	25938	0.51
Fairfield	21186	0.42
Florence	137276	2.70
Georgetown	62992	1.24
Greenville	519178	10.22
Greenwood	69338	1.37
Hampton	19227	0.38
Horry	344865	6.79
Jasper	28363	0.56
Kershaw	64989	1.28
Lancaster	94653	1.86
Laurens	67148	1.32
Lee	16730	0.33
Lexington	291723	5.74
McCormick	9584	0.19
Marion	29585	0.58
Marlboro	26912	0.53
Newberry	37842	0.75
Oconee	77932	1.53
Orangeburg	84909	1.67
Pickens	129617	2.55
Richland	414719	8.17
Saluda	19008	0.37
Spartanburg	322864	6.36
Sumter	105537	2.08
Union	27306	0.54
Williamsburg	31279	0.62
York	276569	5.45